Light and Life:

Vision, Photosynthesis, DNA and Melanoma

MBB 109

Monday, Wednesday, Friday: 10:00-11:00 AM

84 Hall Atwater

Fall 2000

Course Syllabus

Instructor:Ishita Mukerji

Office: Hall Atwater 212

Telephone: 685-2422 (office)

E-mail: imukerji@wesleyan.edu

Office Hours: Mondays: 4:00-5:00 PM

Thursdays: 3:00-4:00 PM or by appointment

Students are strongly encouraged to meet with either the TA’s or myself. If you cannot make the scheduled office hours, we are always available at other times by appointment. Questions can be directed to us either by email or through the Webboard (see below).

Teaching Assistants: E-mail: hpogemiller@wesleyan.edu

Office hours: Tuesdays 2:00 - 4:00 PM Science Library


Web Based Material

E-mail:hpoeng@wesleyan.edu Prerequisites:There are no prerequisites for this course. This general education course is designed for non-majors and others who are interested in how light plays a role in biological processes. A good background in science is desirable; however, the most important prerequisite is a desire to understand the significance of light in the world around us. Interested, highly motivated students without a strong background in science should do well in the course.
 
 

Class Meetings:Regular class meetings are Monday, Wednesday and Friday at 10:00 am in Hall-Atwater 84. Special classes such as guest lectures or computer workshops may take place outside of regular class hours.

Course Description: This course is designed to introduce students to biological processes mediated by light. Topics will include the vision process, photosynthesis, UV-mediated DNA damage and repair processes. We will cover the nature of light and its interaction with matter as an introduction to understanding these major topics in photobiology. The structure of the biological macromolecules that are integral components of these biological processes will be studied to understand the mechanism. We will also discuss the role of light in the onset of melanoma and the release of melatonin. In addition, the depletion of the ozone layer and the consequences of this depletion within the context of health problems associated with increased exposure to UV light will also be discussed. This course provides an introduction to the importance of light for basic biological processes and the dangers of overexposure. Required Texts: There is no required text for the course. The course will cover a distribution of topics, which are not adequately represented in any one textbook. Articles pertinent to the topics discussed in class will be distributed. These articles will be from journals such as Scientific American, The New Scientist, Science, and Nature as well as the reference texts (see below). Any materials given to you in class should be kept in a 3-ring binder. With these items you will construct your own textbook for the course. Reference and Related Texts: Course Outline: A course outline is attached to provide you with a general sense of the direction of the course and the topics to be covered over the course of the semester. It is possible that changes will be made to the course outline - if major changes are made to the outline, a new outline will be distributed. Grading and Evaluation: Your performance in this course will be evaluated on the basis of your class attendance, your participation in class discussion, problem sets, two midterm exams and a final project. The percentage breakdown of your grade is the following:
  • class participation and problem sets
10%
  • paper 
15%
  • midterm exams (2 at 25% each)
50%
  • final project
25%
Regular class attendance will be extremely important, as the class will not be using a standardized textbook. Some of the materials will only be discussed in class and will not be covered in the readings. A student with more than 3 unexcused absences will be dropped from the course. Problem Sets: There will be a weekly set of questions related to course material and the reading. These questions will focus on the concepts presented in class and in the reading. Your responses to these questions should be mainly descriptive and not numerical in nature. Both your questions and responses may be submitted using a Web-based conferencing system, Webboards (http://webboard.wesleyan.edu:5000/~mbb1092000f/login). The advantage of this system is that it allows you to read and respond to the answers of your peers. In many cases the questions will not have one single right answer and by using this system we will be able to have threaded discussions regarding course material and the reading. A training session on how to use this system has been scheduled. Final Project: This course will have a final project in lieu of a final exam. The final project will consist of the construction of a web page that illustrates one or two of the topics covered in class. For example, an appropriate web page might explain the source of color in flowers, what colors bees and other insects actually see and provide instructions on how to perform experiments demonstrating one or more of the fundamental ideas in the page. You will be given information on how to create a web page in class. Although you will be graded on the final outcome, constructing these web pages should be a fun and creative endeavor for you. Design of the course: This course is designed to give you an introduction to science in the world around us, particularly in the area of life processes that are light-driven. In order to understand these fundamental processes such as vision and photosynthesis, we will begin by understanding the nature of light and color. As many of the current health and environmental problems in the world are related to increased UV exposure, the aim of this course is to provide you with a scientific framework in which to comprehend these light-related effects. Within this context of health and environmental problems related to UV exposure, we will discuss processes such as reduction of the ozone layer, DNA damage and melanoma. By the end of the course, you should be able to understand the relationship between light and color, why we see the colors we do, how light interacts with living matter and why the loss of the ozone layer can have serious biological consequences. As some of the teaching approaches are being used for the first time, such as Webboards, your input as a student is valuable and we encourage you to let us know how you think the course is progressing.